Plague is caused by Yersinia pestis, a zoonotic microorganism generally found in mammals and fleas. Individuals contaminated with Yersinia pestis frequently show symptoms after an incubation time of one to seven days. The three fundamental clinical types of plague diseases are bubonic, pneumonic, and septicemic. Bubonic plague is the most common type and is characterized by swollen lymph hubs or buboes.
Plague is transmitted among animals and people through flea-bites. It can be a severe disease in individuals, with a case-casualty proportion of 30% to 60% for bubonic plague, and if it is untreated, it can be lethal. It is an infectious disease and can trigger widespread epidemic through individual-to-individual contact by means of droplets in air. Antibiotic treatment is effective against plague microorganisms.
Based on therapeutic type, the global plague therapeutics market can be bifurcated into vaccine and drugs. The drugs segment is likely to expand at a significant pace during the forecast period because of the wide availability and use of antibiotic drugs for treatment. The vaccine segment can be classified into live attenuated vaccine, recombinant vaccine, and inactivated vaccine. The live attenuated vaccine segment is likely to grow at a rapid pace during the forecast period, as live attenuated vaccines have high antigenic properties which provide a prolonged stimulation to the immune system against plague. In terms of distribution channel, the global plague therapeutics market can be divided into hospital pharmacies, retail pharmacies, and others. The hospital pharmacies segment is likely to expand at a significant pace during the forecast period, as several types of drugs and vaccines are widely available in hospital pharmacies. Moreover, during pneumonic plague, a patient needs antibiotic within 24 hours to prevent death. Hence, patients prefer hospital pharmacies.
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In terms of region, the global plague therapeutics market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America dominates the global plague therapeutic market. The region is projected to account for a significant share of the global plague therapeutic market during the forecast period due to increase in adoption of companion animals in households and high prevalence of plague diseases in rural & semi-rural areas especially in Southwest U.S. Europe is next lucrative plague therapeutic market for plague therapeutics. Availability of different types of plague vaccines, rise in awareness about plague diseases in countries such as China, India, Mongolia, and Vietnam makes Asia Pacific a promising plague therapeutic market for plague therapeutics during the forecast period. Advancements in drug delivery system, rise in awareness about plague immunization, and high prevalence of plague disease in sub-Saharan Africa are likely to augment the plague therapeutics market in Middle East & Africa during the forecast period.
Key players operating in the global plague therapeutics market are iBio, Inc., DynPort Vaccine Company LLC, Bayer Healthcare, Pfizer, Inc., and AstraZeneca, among others.
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